Tag Archive for: Weight loss

Hot topic: Can GLP-1s prevent cancer?

There’s now a good deal of observational data suggesting that GLP-1s do indeed cut the chance of developing obesity-related cancer – possibly by up to 40 per cent.  But we all know that correlation and causation are not the same thing.  So a group of Manchester University academics is planning to run a large study aimed at producing a definitive answer.  They […]

Atrogi announces first subjects dosed in human trial for lead candidate ATR-258

First-in-class oral therapy ATR-258 mimics the effects of exercise – driving fat loss, increasing muscle, and improving metabolism – with broad potential as a novel treatment for muscle-sparing weight loss Study led by Associate Professor Morten Hostrup, a leading authority on β2-adrenergic receptor signaling in skeletal muscle at the University of Copenhagen, to evaluate muscle […]

Hot topic: What if weight loss drugs are just the first longevity game-changers?

Back in mid-January Optimum’s Hot Topics column took a look at life expectancy data and asked the rather depressing question: “Will you live longer than your parents – or not?”  Why so downbeat? Because besides stalling life expectancy figures, a slew of other data also seemed to hint that longevity might have peaked: steadily growing […]

Hot topic: Why it’s best not to ‘go it alone’ with GLP-1 weight loss drugs

OZEMPIC, Wegovy, Mounjaro, Zepbound: they’ve quickly become part of our vocabulary.  In just a few years, powerful GLP-1 drugs, first introduced to control Type 2 diabetes but now much better known for their ability to help people rapidly lose weight, have become indispensable weapons in the Battle of the Bulge.  In the UK alone, some […]